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Chemical Composition. Gabapentin is also known by the chemical name, Aminomethyl cyclohexaneacetic acid. This chemical is the active ingredient in Neurontin. Ingredients of each Neurontin capsule contains Gabapentin of varying strengths -100 mg, 300 mg, or 400 mg. Chemical composition of gabapentin Gabapentin, also known by its brand name Neurontin, is an anticonvulsant medication that is primarily used to treat epilepsy and neuropathic pain. It is a structural analog of the neurotransmitter γ-aminobutyric acid (GABA) but does not bind to GABA receptors directly. Gabapentin is a new chemical compound designed as a structural analog of GABA that is effective in the treatment of partial seizures. In contrast to GABA, gabapentin readily penetrates the blood–brain barrier. In man, gabapentin has been demonstrated to increase GABA concentrations [126]. Most probably the mechanism of action is related to ChemSpider record containing structure, synonyms, properties, vendors and database links for Gabapentin, 60142-96-3, UGJMXCAKCUNAIE-UHFFFAOYSA-N The composition of gabapentin is essential for both healthcare providers and patients to know, as it influences dosing, efficacy, and the likelihood of adverse reactions. The Active Ingredient: Gabapentin. Gabapentin itself is the primary active ingredient in this medication. Gabapentin | C9H17NO2 | CID 3446 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Gabapentin is eliminated from the systemic circulation by renal excretion as unchanged drug. Gabapentin is not appreciably metabolized in humans. Gabapentin elimination half-life is 5 to 7 hours and is unaltered by dose or following multiple dosing. Gabapentin elimination rate constant, plasma clearance, and renal clearance are directly Conversely, gabapentin was first synthesized to be a GABA analog. However, gabapentin does not possess the same chemical composition or capacity as GABA. Gabapentin was designed to more readily cross the blood–brain barrier (BBB), in contrast to GABA, and its initial application was in the treatment of epilepsy [3]. The active ingredient in gabapentin capsules is gabapentin, which has the chemical name 1-(aminomethyl) cyclohexaneacetic acid. The molecular formula of gabapentin is C 9 H 17 NO 2 and the molecular weight is 171.24. The chemical structure of pregabalin is C 8 H 17 NO 2 and has a chemical name of (S)-3(aminomethyl)-5-methylhexanoic acid. Pregabalin has a molecular weight of 159.23 grams per mole. Gabapentin is described as 1- (aminomethyl)cyclohexaneacetic acid with a molecular formula of C9H17NO2 and a molecular weight of 171.24. The structural formula of gabapentin is: Gabapentin, USP is a white to off-white powder with a pKa1 of 3.7 and a pKa2 of 10.7. Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid that was first approved for use in the United States in 1993. 16 It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures 14,5 - today it is also widely used to treat neuropathic pain. 8,10 Gabapentin has Gabapentin hydrochloride | C9H18ClNO2 | CID 6453919 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. The molecular formula of gabapentin is C9H17NO2 and the molecular weight is 171.24. Gabapentin is a white to off-white crystalline solid with a pKa1 of 3.7 and a pKa2 of 10.7. It is freely soluble in water and both basic and acidic aqueous solutions. Gabapentin closely resembles pregabalin, a schedule V drug under the Controlled Substances Act in its chemical structure and pharmacological activity. The chemical structure of gabapentin is derived from the addition of a lipophilic cyclohexyl group to the backbone of GABA. Gabapentin's chemical name is 1-(aminomethyl)cyclohexaneacetic acid; with a molecular formula of C 9 H 17 NO 2 and a molecular weight of 171.24 g/mol. The active ingredient in gabapentin tablets is gabapentin, USP which has the chemical name 1-(aminomethyl)cyclohexaneacetic acid. The molecular formula of gabapentin is C9H17NO2 and the molecular weight is 171.24. Gabapentin (CAS 60142-96-3) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook. The active ingredient in NEURONTIN capsules, tablets, and oral solution is gabapentin, which has the chemical name 1-(aminomethyl)cyclohexaneacetic acid. The molecular formula of gabapentin is C 9 H 17 NO 2 and the molecular weight is 171.24. Chemical structures of GABA and gabapentin, with commonalities highlighted. Gabapentin is a 3,3-disubstituted derivative of GABA. Therefore, it is a GABA analogue, as well as a γ-amino acid. [102] [103] It is similar to several other compounds that collectively are called gabapentinoids.
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