Along with causing dizziness, gabapentin can worsen your coordination. This can increase your risk of falls, which is especially dangerous for older adults. If you’re just starting to take gabapentin or your dose has increased, avoid driving or doing any activity that requires alertness. Not everyone who takes gabapentin will experience changes in blood pressure. However, certain factors may increase your risk, including: * Age: Older adults may be more susceptible to blood pressure changes. * Existing blood pressure issues: If you already have high or low blood pressure, gabapentin may exacerbate these issues. losartan, a medication used to treat high blood pressure ethacrynic acid (Edecrin), a diuretic medication used to treat fluid retention ( edema ) phenytoin (Dilantin), a medication used to treat We have explained how gabapentin can cause high blood pressure. However, not every individual taking gabapentin would experience high blood pressure or the same side effects. Other factors can increase one’s risk of high blood pressure besides gabapentin. Research on rats has shown that gabapentin may lower blood pressure in those with high blood pressure (hypertension). Does gabapentin cause constipation? One of the possible side effects of Yes, it can cause High Blood Pressure (hypertension) Cardiovascular side effects including hypertension have been reported to occur in more than one percent of patients taking gabapentin. Read more at: The medication list, presented in Additional file 1: Table S2, includes the medications for diabetic neuropathy, medications that can cause fluid retention and medications that can raise the blood pressure. (B) Effects of unilateral NTS microinjection of gabapentin on MBP and HR. BP, blood pressure; MBP, mean blood pressure; HR, heart rate recorded at paper speed of 3 mm/min. Horizontal bar represents recording during 5-min intervals. * p < 0.05 vs. vehicle group, n = 3. Gabapentin induced systemic vasodepressor effects through NOS in the NTS Experts believe gabapentin may cause brain cells to produce more of a chemical called GABA, which reduces abnormal electrical activity of brain cells. In people experiencing nerve pain after having had shingles, gabapentin is thought to change the way pain signals are sent through the body and brain. Research suggests that gabapentin can lower blood pressure by reducing the body’s production of certain hormones that can increase blood pressure. It may also help to relax blood vessels, making it easier for blood to flow through them. Can gabapentin cause high blood pressure? Yes, abruptly stopping gabapentin can lead to rebound hypertension , a withdrawal symptom. Additionally, while not a direct cause, the cardiovascular risks associated with long-term use can indirectly affect blood pressure. Gabapentin is associated with a risk of dependence and withdrawal. Abrupt discontinuation of the drug may result in symptoms similar to those of benzodiazepine or alcohol withdrawal and may include: Hypertension (high blood pressure). Sweating. Confusion. Incoherent speech. Impaired ability to pay attention. Nausea. Pain. Insomnia. Restlessness Background Gabapentin and pregabalin are commonly prescribed medications to treat pain in patients with diabetic neuropathy. Gabapentin and pregabalin can cause fluid retention, which is hypothesized to be associated with cardiovascular diseases. However, whether long-term use of gabapentin and pregabalin is associated with adverse cardiovascular diseases remains unknown. This study aims to 2. Can Gabapentin cause high blood pressure? While some studies suggest gabapentin may have therapeutic benefits for individuals with hypertension, it does not typically cause high blood pressure. It is important to monitor blood pressure when taking gabapentin, especially in patients with a history of hypertension, but gabapentin is not a The medicine works best if a constant amount is in the blood. Neurontin® capsules, tablets, and solution. may be taken with or without food. You may break the scored . Neurontin® tablets into two pieces, but make sure you use the second half of the tablet as the next dose. Do not use the half-tablet if the whole tablet has been cut or broken The oral solution contains 250 millgrams of gabapentin per 5 milliliter (50 mg per mL) Neurontin or generic gabapentin. Gabapentin capsules. It’s available as 100-, 300- or 400-milligram gelatin capsules (Neurontin or generic gabapentin). High blood pressure is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Rheumatoid arthritis. While studies suggest that gabapentin can lower blood pressure and heart rate acutely, it is also listed as a potential side effect to cause hypertension, or high blood pressure, particularly with long term use. When you stop taking gabapentin, you'll need to reduce your dose gradually to avoid withdrawal symptoms. Do not stop taking gabapentin without talking to your doctor. Talk to your doctor if you're concerned about becoming physically dependent on gabapentin. Other side effects. These are not all the side effects of gabapentin. Pain and blood pressure appear to be strictly related. According to available evidence, both pain and analgesic therapies may induce a clinically significant destabilization of blood pressure values. The subsequent implications on hypertension incidence and blood pressure control remain unclear and should be explored in future studies. Funding
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