Many things can cause tinnitus. And sometimes, tinnitus can occur with no known cause. In any case, tinnitus can affect your quality of life, making it harder to sleep and complete your daily tasks. So, finding out the cause of your tinnitus, if there is one, is important. Medications are one possible cause of tinnitus. Does gabapentin cause hearing loss & tinnitus? Rarely. Gabapentin is more likely to cause tinnitus (ringing in the ears) than hearing loss – but both have been reported in users. Tinnitus, or ringing in the ears, is a listed side effect of Neurontin . Interestingly enough, even though gabapentin can cause ringing in the ears, it is sometimes prescribed off-label for the treatment of it. Nevertheless, the vast majority of studies report that the drug is no more effective than placebo in this regard. Stopping gabapentin suddenly can cause serious problems, like withdrawal symptoms or the return of seizures. Your doctor will help you stop taking the drug safely. Drug interactions Gabapentin can cause a whole host of ear problems including hearing loss, tinnitus, ear pain, ear infections, Otitis externa (ear infections in the outer ear/ear canal) and Otitis media (ear infections in the middle ear) plus a lot more. Areas covered: This article review the evidence that long-term treatment with some antiepileptic drugs (AEDs) [e.g. carbamazepine, phenytoin, valproate, lamotrigine, gabapentin, vigabatrin and oxcarbazepine] (even in therapeutic drug doses) may result in tinnitus, phonophobia, sensorineural hearing loss, dizziness, ataxia, disequilibrium, imbala While it’s not common, some medications can cause hearing loss. Examples include certain antibiotics, high doses of aspirin, and water pills (diuretics). Medication-related hearing loss tends to be more common if you take more than one medication that affects your hearing. In many cases, hearing loss caused by medications is mild and reversible. Can gabapentin cause hearing problems? Normal doses for the treatment of diabetic peripheral neuropathy range from 900 to 3600 mg/d divided 3 times daily. Conclusions: We report a patient with acute renal failure who developed hearing loss, myoclonus, and confusion with hallucinations in the presence of elevated gabapentin concentrations. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Prolonged use can cause hearing problems, such as tinnitus. These problems are usually temporary and resolve on their own after stopping the medication. One study from 2023 showed that frequent users of acetaminophen may be at higher risk of persistent tinnitus. More rarely, gabapentin can cause fluid buildup (edema), weight gain, and vision problems. It can also cause diarrhea. More serious (but rare) side effects include suicidal thoughts or behavior, and mood changes in children. However, these studies utilized a single drug dose and did not include objective measures of tinnitus loudness. While one study showed no significant difference in overall tinnitus severity between placebo and gabapentin groups, a significant improvement was observed in participants with normal hearing in the gabapentin group. Can Gabapentin Cause Loss of Hearing? Yes, gabapentin can cause loss of hearing. Research has shown a connection between gabapentin use and reversible hearing loss, especially in patients with renal impairment. The toxic effects of gabapentin, when kidneys are compromised, can lead to this issue. Has anyone had severe tininitus caused by gabapentin? I have been on 1200mg/day of gabapentin for a couple of months now, and I have had a severe roaring in my ears for about a month. I also have pain. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Related studies Sudden hearing loss in Gabapentin; How the study uses the data? The study is based on gabapentin (the active ingredients of Gabapentin). Other drugs that have the same active ingredients (e.g. generic drugs Gabapentin is already on the list of drugs that can cause auditory hallucinations. In fact, hundreds and hundreds of people have reported hearing phantom sounds as a result of taking this drug. It also causes hearing loss in even more people. It’s never a good idea to go off a drug “cold turkey” when you’ve been on it for a while. Moreover similar to lidocaine, gabapentin can inhibit voltage-activated Na + channels . A study in rat models revealed that administration of salicylates decreases GABA and the affinity of the GABA receptors in the brain and induces the sensation of tinnitus and hearing loss ( 12 ). Experts believe these medications interfere with the ionic composition of the fluids in the ear, contributing to hearing loss. Although loop diuretics can cause permanent damage if you get a large dose by injection in the hospital, in most cases, they cause only temporary hearing loss that clears up once you stop using the drug. We report a patient with acute renal failure who developed hearing loss, myoclonus, and confusion with hallucinations in the presence of elevated gabapentin concentrations. Due to rapid improvement after hemodialysis and discontinuation of gabapentin, we believe that these symptoms were probably due
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