Overall, gabapentin does not raise blood pressure; in fact, it tends to lower BP, particularly in hypertensive models and during stress-inducing procedures like surgery. Its hypotensive effects are primarily mediated through the sympathetic nervous system and central mechanisms involving the NTS. Summary: High blood pressure is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Rheumatoid arthritis. Gabapentin is used to control seizures, to treat nerve pain that can happen after having had shingles, and to treat a condition called restless legs syndrome. In addition to these FDA-approved uses, doctors sometimes prescribe gabapentin off-label. Like all medicines, gabapentin can cause side effects, although not everyone gets them. These common side effects of gabapentin may happen in more than 1 in 100 people. They're usually mild and go away by themselves. There are things you can do to help cope with them: As your body gets used to gabapentin, these side effects should wear off. Gabapentin is a drug for nerve pain regulation that can cause high blood pressure when withdrawn abruptly or cause insomnia. Learn about other factors that can increase your blood pressure risk and how to recognize the signs of hypertension. The relationship between gabapentin and blood pressure is complex, as the drug may exert both hypertensive and hypotensive effects depending on the patient’s clinical context and individual response. In some cases, gabapentin has been reported to cause a decrease in blood pressure, particularly in patients with autonomic dysfunction or those Can gabapentin cause high blood pressure? Yes, abruptly stopping gabapentin can lead to rebound hypertension , a withdrawal symptom. Additionally, while not a direct cause, the cardiovascular risks associated with long-term use can indirectly affect blood pressure. Gabapentin can cause increases or decreases in blood pressure in some people, depending on various factors. Learn how to manage your medication concerns with Statcare's urgent care, primary care, and virtual care services. More rarely, gabapentin can cause fluid buildup (edema), weight gain, and vision problems. It can also cause diarrhea. More serious (but rare) side effects include suicidal thoughts or behavior, and mood changes in children. Oral and intravenous gabapentin can markedly attenuate blood pressure (BP) in hypertensive rats. The nucleus tractus solitarii (NTS) is the primary integrative center for cardiovascular control and other autonomic functions in the central nervous system. Yes, gabapentin can lower blood pressure. However, in the vast majority of people taking gabapentin, it does not lower blood pressure to a worrisome extent. A blood pressure of 113/64 is below average, but it is not at a worrisome level unless it is associated with any lightheadedness or dizziness. Blood Pressure Monitoring: Regularly monitor blood pressure to detect any increases. Cholesterol Monitoring: Gabapentin may increase LDL cholesterol, so regular monitoring is important. Open Communication: Inform your doctor about any changes you experience, such as swelling, palpitations, or chest pain. One possible explanation for the findings is that gabapentin and pregabalin can alter arterial myogenic tone and cause fluid retention . Fluid retention causes either an increase in cardiac output or an increase in blood pressure . Velocity of blood flow increases either way, thereby increasing turbulence of blood flow . Yes, it can cause High Blood Pressure (hypertension) Cardiovascular side effects including hypertension have been reported to occur in more than one percent of patients taking gabapentin. Read more at: 2. Can Gabapentin cause high blood pressure? While some studies suggest gabapentin may have therapeutic benefits for individuals with hypertension, it does not typically cause high blood pressure. It is important to monitor blood pressure when taking gabapentin, especially in patients with a history of hypertension, but gabapentin is not a Although gabapentin can cause several adverse reactions, many people experience no serious side effects from this drug. Gabapentin reduces blood pressure and heart rate through the nucleus The Risks of Taking Gabapentin for High Blood Pressure. Research indicates that gabapentin can cause blood pressure to rise in some cases, which may be due to its effects on the body’s blood vessels. When blood vessels constrict, blood pressure can increase, leading to potential complications. The current body of research indicates that gabapentin does not increase blood pressure. Instead, it generally lowers BP, particularly in hypertensive conditions, by modulating sympathetic nervous system activity and central cardiovascular control mechanisms. In conclusion, while Gabapentin can potentially cause a slight increase in blood pressure, this side effect is generally manageable and does not pose a significant risk to most individuals. However, it is important to be aware of the potential connection and to monitor your blood pressure regularly while taking Gabapentin. Both pain and analgesic medications are known to affect blood pressure (BP) values, with pressor effects varying according to pain duration and the drug class considered [8, 9••, 10••]. Consequently, pain and analgesics may potentially influence the development of arterial hypertension and interfere with BP control in hypertensive patients.
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