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Medications that cause weight gain: Several medications can cause weight gain. But some are more likely to do so than others. Gabapentin side effects: Weight gain is a possible gabapentin side effect, though it’s not the most common. Drowsiness, dizziness, and swelling are more likely. I have been on Gabapentin 2400 mg per day and have gained 30 pounds in a short time and just wanted to know if this med causes the weight gain or is it just due to me eating more. Answer. Yes, weight gain is a possible side effect for gabapentin (brand name Neurontin). The incidence of weight gain with gabapentin varies by product: Yes, gabapentin can cause weight gain. One review article looking at weight gain from medications found an average weight gain of almost 5 pounds after just 1.5 months on gabapentin. Although the drug can be highly effective for some individuals in the treatment of various types of pain, as well as reducing the occurrence of seizures, many people are dissatisfied with the drug’s side effect profile. One of the most distressing side effects that people experience is that of weight gain. Lyrica and Weight Gain Lyrica may cause weight gain, but it’s not exactly known why. It may be related to the fact that Lyrica can increase your appetite. Weight gain can also occur with edema. The longer you take Lyrica, the more likely weight gain may be. It’s also more likely with higher doses (300 mg daily or more). A review of research examining antipsychotic medicine explains why: Most of those drugs cause weight gain. Over the course of treatment, around 7 in 10 patients will gain weight — rapidly in the initial period after starting these meds, but it continues over the long term. The risk appears to be highest with: Olanzapine (Zyprexa) Clozapine Lyrica and its popular predecessor Gabapentin (Neurontin) have both been shown to cause significant weight gain. In a 2008 study, patients taking Lyrica for epilepsy, gained approximately 4 kg (8 lb) in a 3 to 6-month period. One side effect that’s more common with pregabalin is weight gain. This side effect doesn’t appear to be linked to fluid buildup, but it’s something to pay attention to if you’re starting pregabalin. Lyrica (pregabalin) is a prescription drug that’s prescribed to treat nerve pain, fibromyalgia, and seizures in certain situations. Lyrica can cause side effects that range from mild to serious. Lyrica (pregabalin) and weight gain. Weight gain is one of the possible side effects of taking pregabalin (Lyrica) as prescribed. However, the majority of patients prescribed Lyrica won’t gain weight or will gain only a small amount. The reported incidence of weight gain from Lyrica ranges from 2% to 14.8% of patients. Since a greater percentage of Lyrica users gain weight, and Gabapentin is similar – some believe that the reports of weight gain on Gabapentin are low-ball estimates. Despite these theories, the bulk of scientific evidence suggests that most people will not gain significant weight while taking Gabapentin. Lyrica vs Gabapentin: What's the difference? How long does it take for Lyrica to work? Does Lyrica cause weight gain? How long does Lyrica stay in your system? Can you stop Lyrica cold turkey? Is Lyrica a controlled substance / narcotic? Does Lyrica make you sleepy? Is there a generic for Lyrica? What is Lyrica used to treat? Lyrica is more likely than gabapentin to cause side effects such as dry mouth, constipation, swelling (edema), breast enlargement, or weight gain; Gabapentin is more likely than Lyrica to cause side effects such as difficulty speaking, fever, an increased risk of viral infections, unusual eye movements, or jerky movements Gabapentin may cause weight gain, but it is an uncommon side effect. Studies have shown that a small number of people taking gabapentin, a drug used to treat epilepsy and postherpetic neuralgia, experienced weight gain. People who do gain weight may gain about 5 pounds after 6 weeks of use. This is not the case however. Gabapentin is the generic of a different medication, Neurontin. Nevertheless, the chemical structures of Lyrica and gabapentin are nearly identical to one another. The main difference between the two medications is that Lyrica is more potent, and lasts longer per dose than gabapentin. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. Rare but serious gabapentin side effects include mood changes in children. It can also cause suicidal thoughts or behaviors in children and adults. These “gabapentinoids” can cause a large number of side effects. Weight gain is surprisingly common among people taking Lyrica. Other common Lyrica side effects include fatigue, vertigo, brain fog, fluid retention, dry mouth, blurred vision, constipation, gas, depression, tremor and skin rash. Weight gain is a common side effect associated with Lyrica treatment. In studies, 9% of Lyrica-treated patients and 2% of placebo (inactive treatment) patients gained 7% or more compared to their weight at the beginning of the study. Lyrica is also linked with an increase in appetite and fluid retention. Yes, pregabalin can cause weight gain, with about 9% of patients experiencing an increase of 7% or more of their initial body weight. Pregabalin weight gain is usually moderate, with an average gain of around 1.6 kg (3.5 lbs) in clinical trials. Weight gain is not considered a common side effect of gabapentin. In clinical trials, only about 2% of people reported weight gain with its use. In people who do gain weight while on gabapentin, a research study showed a weight gain of about 5.5 pounds after 1.5 months of use.
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