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Are there any serious interactions with gabapentin and other medications? Serious breathing problems can happen if you take gabapentin with drugs that cause severe sleepiness or decreased awareness. Some examples include narcotic opioids, anti-anxiety medicines, antidepressants, and antihistamines. 270 medications are known to interact with gabapentin. Includes: drug, food, pregnancy, breastfeeding and therapeutic duplication warnings. Neurontin: 100 mg, 300 mg, 400 mg. Consult drug interactions database for more detailed information. Dosage form specific issues: Product interchangeability In a single (400 mg) and multiple dose (400 mg three times a day) study of GABARONE in epileptic patients (N=8) maintained on phenytoin monotherapy for at least 2 months, gabapentin had no effect on the steady-state trough plasma concentrations of phenytoin and phenytoin had no effect on gabapentin pharmacokinetics. Carbamazepine Neurontin drug interactions. There are 270 drug interactions with Neurontin (gabapentin). Neurontin disease interactions. There are 4 disease interactions with Neurontin (gabapentin) which include: drug dependence; renal dysfunction; suicidal tendency; hemodialysis NEURONTIN is contraindicated in patients who have demonstrated hypersensitivity to the drug or its ingredients. When gabapentin and magnesium-containing medications or supplements are combined, they may interact. Here, we’ll walk through the interaction between gabapentin and magnesium and how to safely take both if they’re recommended by your healthcare provider. Gabapentin, like any other substance, can interact with other substances. Those taking gabapentin should therefore always disclose to their doctors any medical conditions, other medications (prescription or over the counter), supplements, herbal products, illicit drugs, tobacco products, alcoholic beverages, and dietary choices. Gabapentin belongs to the class of medications called anti-epileptics. It is used in combination with other seizure control medications to manage and prevent seizures associated with epilepsy. Gabapentin does not cure epilepsy and only works to control seizures as long as the medication is taken. In a single (400 mg) and multiple dose (400 mg three times a day) study of GABARONE in epileptic patients (N=8) maintained on phenytoin monotherapy for at least 2 months, gabapentin had no effect on the steady-state trough plasma concentrations of phenytoin and phenytoin had no effect on gabapentin pharmacokinetics. Carbamazepine Your doctor or pharmacist can provide more information on specific drug interactions that may pertain to you. Gabapentin can interact with several medications, leading to different effects. One important interaction is with opioids, such as morphine or oxycodone, which can cause severe sleepiness, respiratory depression, coma, or even death. A Cochrane review reported that 3 to 4 patients out of every 10 with either of these conditions experienced at least a 50% reduction in pain intensity when prescribed gabapentin at dosages of 1800mg-3600 mg/day (gabapentin encarbil: 1200mg-3600 mg/day). This compared with only 1 or 2 out of every 10 given a placebo (an inactive treatment). Some of the main substances that interact with gabapentin are morphine, caffeine, losartan, ethacrynic acid, phenytoin, mefloquine and magnesium oxide. Some of the side effects caused by gabapentin are teratogenicity, hypoventilation, respiratory failure and myopathy. Does gabapentin interact with other medicines (drug interactions)? Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, Each Neurontin capsule contains 100 mg, 300 mg, or 400 mg of gabapentin and the following inactive ingredients: lactose, cornstarch, talc, gelatin, titanium dioxide, FD&C Blue No. 2, yellow iron oxide (300 mg and 400 mg only), and red iron oxide (400 mg only). Each Neurontin tablet contains 600 mg or 800 mg of gabapentin and the following In a single (400 mg) and multiple dose (400 mg three times daily) study of gabapentin immediate release in epileptic patients (N=8) maintained on phenytoin monotherapy for at least 2 months, gabapentin had no effect on the steady-state trough plasma concentrations of phenytoin and phenytoin had no effect on gabapentin pharmacokinetics. Gabapentin is a prescription drug most commonly prescribed to relieve nerve pain following shingles in adults and the pain of postherpetic neuralgia. Learn about side effects, drug interactions, dosages, warnings, and more. Each NEURONTIN capsule contains 100 mg, 300 mg, or 400 mg of gabapentin and the following inactive ingredients: cornstarch, FD&C Blue No. 2, gelatin, lactose, red iron oxide (400 mg only), talc, titanium dioxide, and yellow iron oxide (300 mg and 400 mg only). Each NEURONTIN tablet contains 600 mg or 800 mg of gabapentin and the following Of the total drug interactions, 25 are major, 34 are moderate, and 8 are minor. Does acyclovir interact with my other drugs? Acyclovir 400 mg (J 49) View larger Does gabapentin interact with my other drugs? Enter medications to view a detailed interaction report using our Drug Interaction Checker.
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