gabapentin and leg swelling can gabapentin cause weight loss

He noticed significant leg swelling almost immediately upon starting treatment; this persisted for nearly three weeks before gradually improving after his doctor reduced his dosage. These cases highlight how individual responses vary widely based on dosage levels and personal health backgrounds while using gabapentin. Gabapentin is a common medication-related cause of peripheral edema. This is when you experience swollen tissues in the body, often in the arms and legs. Up to 8% of people report edema with gabapentin clinical studies. But it’s more likely to occur in older adults. Will swelling go away while taking gabapentin 200 mcg at bedtime. I was on this medication for quite awhile and it did cause a lot of swelling. Then I started gaining weight and I was tired all the time. I had many other bad side effects so I’m tapering off it now. I wish that I had never started taking it. Seven days after the administration of the gabapentin, the patient complained from pain and edema and scaling and hyperesthesia in his lower extremities and pitting edema, pain and tenderness. The range of motion of the extremities was been increased. We study how severe was Foot, leg, and ankle swelling, when it was recovered, drug effectiveness, race, and more among people who take Gabapentin (gabapentin). This phase IV clinical study is created by eHealthMe based on reports submitted to eHealthMe, and is updated regularly. When you stop taking gabapentin, you'll need to reduce your dose gradually to avoid withdrawal symptoms. Do not stop taking gabapentin without talking to your doctor. Talk to your doctor if you're concerned about becoming physically dependent on gabapentin. Other side effects. These are not all the side effects of gabapentin. I've been taking gabapentin for many years.Only recently I figured out that my blood pressure meds were causing swelling.I stopped taking them and it got better.Im a ex combat medic and I lost one leg in the gulf war.Recently I ran out of gabapentin and I thought wow my one leg has no swelling at all.i have a burn that has a hard time healing Swelling in the feet and ankles. Patients taking Neurontin may experience swelling in the feet and ankles. The presence of lower leg swelling may cause discomfort and impair walking. My mother-in-law was unable to wear regular shoes because of swelling of her feet and ankles, so we found her socks and soft slippers that fit her feet comfortably. I take 600 mg of gabapentin, 300 mg twice daily. No swelling in my feet. I still get some cramping and stabbing. I hope everything is going well with others. I have swelling in my legs caused by lymphedema and have to wear compression socks but mine was not caused by a medication. I also would be concerned if it's been over 5 months since stopping gabapentin and the swelling and pain is still in the hands and feet. diabetic neuropathy, which is associated with multiple co-morbidities that can give rise to bilateral leg swelling. Presence of gabapentin induced leg swelling can thus confound the clinical picture. Key words: Edema, gabapentin, lower extremity Introduction Gabapentin was originally developed as a muscle relaxant/anti‑spastic agent. In the literature, pregabalin-induced peripheral edema is dose-dependent [4] whereas it is less pronounced for gabapentin [29], [30], [31]. Gabapentin has non-linear pharmacokinetics, so the dose-ADR relationship is likely to be attenuated. Indeed, due to its saturable absorption, high plasma exposure values are more difficult to obtain [32 This is a case of painful, 4+ pitting bilateral edema with a probable association to gabapentin (Naranjo score 5) and a clear dose relationship in a patient with pervasive developmental disorder and schizoaffective disorder utilizing gabapentin for mood stabilization. Managing gabapentin-induced edema requires a multi-faceted approach, considering both lifestyle modifications and potential medication adjustments. Our article will provide practical tips and strategies that can help alleviate and manage the swelling effectively. We present a rare case of gabapentin induced bilateral 3+ pitting edema in a young man with sensorimotorpolyneuropathy, making it an unusual presentation. The authors reported bilateral pretibial edema after 3 weeks of gabapentin 300 mg/d for neuropathic pain. Within 3 days of discontinuation of gabapentin, the edema resolved. When the patient was rechallenged with gabapentin, the edema returned after 5 days, suggesting the authors' suspicions of an adverse effect from gabapentin was likely correct. This is clinically important as gabapentin is a very commonly prescribed medication to patients with neuropathies, especially in diabetic neuropathy who may also have other co-morbid condition such as heart failure, malnutrition, nephropathy, that can give rise to bilateral leg swelling. Gabapentin binds to the alpha-2-delta subunit of presynaptic voltage-gated calcium channels and is used for a wide variety of on- and off-label indications. Gabapentin is dosed at total daily doses ranging from 300 to 3600 mg/d, which is generally divided into 3 doses. Although gabapentin is general Amlodipine (Norvasc), gabapentin (Neurontin, Horizant, Gralise), and pregabalin (Lyrica) can cause puffy legs and ankles. Birth control pills, certain over-the-counter pain medications, and steroids are a few other culprits. Edema is a well-described side effect of gabapentinoid drugs (i.e., gabapentin and pregabalin). In this study from Ontario, Canada, researchers used provincial databases to examine whether gabapentinoid use was followed by diuretic prescriptions — a so-called “prescribing cascade” in which a drug is prescribed to treat an adverse effect of another drug.

gabapentin and leg swelling can gabapentin cause weight loss
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