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Results of this study suggested that gabapentin is a safe and effective treatment for cats to help reduce stress and aggression and increase compliance for transportation and veterinary examination. Abstract OBJECTIVE To determine the effects of oral gabapentin administration prior to veterinary examination on signs of stress in cats. DESIGN Randomized, blinded, crossover clinical trial. ANIMALS 20 healthy pet cats with a history of fractious behavior or signs of stress during veterinary examination. PROCEDURES Cats were scheduled for 2 veterinary visits 1 week apart and randomly assigned This study set out to investigate the effect of giving a single dose of gabapentin for fear-based aggressive behaviors in cats during veterinary visits. The researchers compared a dose of either 100 or 200 mg/cat to placebo capsules 2 hours prior to the vet visit. There is moderate to good evidence to indicate that a single dose (100 mg) of oral gabapentin administered to cats might reduce signs of acute stress associated with veterinary visits. Two blinded, randomised, placebo controlled trials were reviewed, with consistency of direction of effect for the main outcome measure (Cat Stress Score) assessed. And it’s a gamechanger when it comes to reducing stress for cats undergoing vet check-ups – research indicates that administering this medication 90 minutes prior to the visit results in far less stress-related symptoms. So, how safe is it? Generally, Gabapentin is safe for cats as long as you follow your vet’s instructions and dosing guidelines. However, in cats, gabapentin is used for chronic musculoskeletal neuropathic pain and mild sedation in stressful situations such as vet visits, travel sickness etc. Knowing about the safe Gabapentin dosage for feline is essential. In cats, gabapentin is most often used as a pain medication for chronic pain, such as from arthritis. Gabapentin is also recognized as beneficial in reducing the fear responses that a kitty may have to the stress of handling and being examined at the vet. Gabapentin is a medication used to treat pain in cats. It is also used as a sedative to help reduce anxiety during stressful situations, like car travel and vet visits. Here’s what you need to know about this common feline medication. What is gabapentin for cats, and how does it work? In cats, single-dose gabapentin (50-100 mg/cat) may result in decreased stress, but not necessarily sedation, 2 to 3 hours after oral administration. Gabapentin may be safely administered before anesthesia and routine surgery in healthy patients older than 4 months. Potential Adverse Reactions to Gabapentin in Cats. Gabapentin for Cats is a versatile pet medication used to manage pain, seizures, and anxiety in felines. However, like any drug, it comes with potential side effects and requires careful consideration and guidance from a veterinarian to ensure it’s administered safely and effectively. Per-protocol analysis showed that gabapentin predicted quicker behavior modification progression and lower cat stress score, latency to emerge, and urine suppression compared to placebo. Median time to graduation was reduced by half with gabapentin. Gabapentin has many useful properties for treating cats beyond use as an anticonvulsant. It is used off-label in cats to reduce situational anxiety, provide pain relief, and is the preferred treatment for a condition called feline hyperesthesia syndrome. Abstract. This review focuses on pre-appointment medications used to decrease fear and anxiety in dogs and cats related to veterinary visits. A review of the literature revealed data on 4 medications from 4 medication classes that have been used to ameliorate acute situational fear and anxiety in dogs and cats: gabapentin, trazodone, oral transmucosal dexmedetomidine, and alprazolam. Anxiety and Stress Reduction: It is increasingly utilized to help cats manage anxiety, particularly in stressful situations like veterinary visits or when introduced to new environments. Seizure Control: As an anticonvulsant, gabapentin may be prescribed to manage seizures in cats, although it is not always the first-line treatment. Overall, the present study yielded good evidence that oral administration of a 100-mg gabapentin capsule to cats 90 minutes before transporting them to the veterinary hospital led to a significant reduction in stress-related behaviors during transportation and examination. A single dose of 100mg/cat was associated with a reduction in the levels of behavioural parameters associated with feline stress, as observed 90 to 180 minutes post-administration of the gabapentin. This effect was observed in cats given gabapentin prophylactically and in cats already showing a behavioural stress response. Effects of a single preappointment dose of gabapentin on signs of stress in cats during transportation and veterinary examination. J Am Vet Med Assoc. 2017 Nov 15;251(10):1175-1181. Stress associated with transportation, examination, and diagnostic procedures is a major barrier that often prevents pet cats from receiving regular veterinary care. Gabapentin, a medication commonly used in cats for various conditions such as chronic pain and anxiety, offers two different forms of administration: oral and transdermal. Each form has its own unique benefits, and understanding the differences can help you make an informed decision about which option is best for your cat. Gabapentin is a versatile and very safe medication for cats, effective in managing pain, anxiety disorders, and behavioral issues. The most common side effect of gabapentin in cats is mild sedation, usually temporary and typically decreases with continued use. Another study evaluated the benefit of gabapentin to reduce stress in a trap, neuter, and return programme. 5 These authors also used a wide dose range of 9-47 mg/kg because of the use of a set size capsule across a range of cat sizes. They noted the greatest effect was at two hours post-administration.
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