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2. Is Gabapentin a controlled substance in North Carolina? • No, Gabapentin is not a controlled substance in North Carolina. 3. Why is Gabapentin included in the NC CSRS if it isn’t a controlled substance? • There is evidence that Gabapentin, when taken with opioids, can increase the risk of unintended overdose. For controlled substance licensure, the rule changes require a designated prescriber to have a controlled substance license for a health facility if substances are stored there without an on-site pharmacy or an automated device stocked by a pharmacy, provide an exception to licensure for an emergency kit that contains controlled substances Gabapentin isn’t a narcotic or federally controlled substance, but it is regulated and recognized as a controlled substance in certain states. Gabapentin is approved by the Food and Gabapentin isn’t a controlled substance according to the federal government. But several states have passed their own laws classifying gabapentin a schedule V (schedule 5) controlled substance. Combining gabapentin and opioids can be extremely dangerous. Gabapentin is not currently controlled under the Controlled Substances Act of 1970. While gabapentin remains a non-controlled substance, Session Law 2023-65 Part XI Section 11.1 G.S. 90-113.73(b) adds it to the medications recorded in NC CSRS because it may cause a level of sedation in patients that puts them at increased risk of overdose when taken with opioids. The NC Department of Health and Human Services (NCDHHS) has The communication stated that practitioners must report all dispensed gabapentin prescriptions to the New Mexico Prescription Monitoring Program (PMP) to facilitate evaluation of potential risk factors for respiratory depression. Gabapentin is not classified as a controlled substance. Gabapentin (Neurontin) is not a narcotic or federally controlled substance by the DEA as of November 2022, but it is classified as a Schedule V controlled substance in certain states. Gabapentin is not currently listed as a controlled substance under the Controlled Substances Act of 1970. 11 Several state boards of pharmacy, as outlined in Supplemental Table 2 and Figure 1, have independently reclassified gabapentin under state pharmacy rules as a Schedule V drug. Other states have required gabapentin use to be monitored The first marketed medication in this class, gabapentin, is not currently classified as a controlled substance in most states, however, its abuse potential is still being investigated. In fact, Kentucky, Michigan, and Tennessee have reclassified gabapentin as a Schedule V controlled substance.⁵˒⁶ January 9, 2019 – In an effort to continue to combat the opioid epidemic in Michigan, the Dept. of Licensing and Regulatory Affairs (LARA), with the support of the Michigan Board of Pharmacy, has modified its Pharmacy Rules to categorize Gabapentin as a Schedule 5 controlled substance. Gabapentin – or Neurontin – is a medication commonly Gabapentin is not a federally-controlled drug substance and does not contain an opioid (narcotic) medication. However, gabapentin misuse and abuse has been reported, and it may be restricted in some states through their state drug-monitoring program. At the national level, gabapentin is not classified as a controlled substance under the Controlled Substances Act (CSA). This means it is not subject to the stringent regulations that apply to opioids or benzodiazepines, which are categorized based on their potential for abuse, medical use, and safety. Twelve states have not classified gabapentin as a controlled substance, but require gabapentin dispensing must be reported to their PMP (including CT, DC, IN, KS, MA, MN, NE, NJ, OH, OR, UT, and WY). Update on Gabapentin in Ohio As a reminder, gabapentin is not considered a controlled substance in Ohio. The Board was made aware of incorrect communications made by a third-party vendor stating that Ohio had made gabapentin a controlled substance. While gabapentin is not a controlled substance, rule 4729:8-2-02 requires the following entities to Gabapentin is not currently listed as a controlled substance under the Controlled Substances Act of 1970.11 Several state boards of pharmacy, as outlined in Supplemental Table 2 and Figure 1, have independently reclassified gabapentin under state pharmacy rules as a Schedule V drug. Other states have required gabapentin use to be monitored Gabapentin is not a controlled substance on a federal level but is controlled in some states, which limits the number of prescription refills and how it is reported. Gabapentin can be dangerous when used in combination with other substances, particularly opioids. Gabapentin is not currently listed as a controlled substance under federal law. However, some states classify gabapentin as a Schedule V substance or a drug of concern and mandate reporting to PMP. Furthermore, other states are considering similar actions due to increasing evidence of associated risks. Gabapentin is not a scheduled controlled substance. Gabapentin closely resembles pregabalin, a Schedule V controlled substance, in its chemical structure and pharmaceological activity. Gabapentin is a prescription medication approved by the Federal Food and Drug Administration Gabapentin has been designated as a monitored prescription drug, not a controlled substance. A DEA registration number is not required for a practitioner to prescribe Gabapentin, nor is a DEA registration number required for a dispenser to fill a prescription for Gabapentin. Practical Impact for Many Prescribers and Dispensers of Gabapentin
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