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Gabapentin is in the drug class gamma-aminobutyric acid analogs. A total of 17 drugs are known to interact with Vitamins. Vitamins is in the drug class vitamin and mineral combinations. Vitamins is used to treat Dietary Supplementation. Generic Name Gabapentin DrugBank Accession Number DB00996 Background. Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid that was first approved for use in the United States in 1993. 16 It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures 14,5 - today it is also widely used to treat neuropathic pain. 8 Alcohol causes a more rapid release of gabapentin enacarbil from the extended-release tablets that may increase the risk for adverse events. In an in vitro dissolution study, 63% of the gabapentin enacarbil dose was released at 1 hour at the highest alcohol concentration studied (40%). Those taking gabapentin should therefore always disclose to their doctors any medical conditions, other medications (prescription or over the counter), supplements, herbal products, illicit drugs, tobacco products, alcoholic beverages, and dietary choices. Use the interactions A to Z to look up a drug and see which other drugs it interacts with and the severity of these interactions. 270 medications are known to interact with Neurontin. Includes: drug, food, pregnancy, breastfeeding and therapeutic duplication warnings. The most well-documented nutrient concern regarding gabapentin is its potential to deplete folic acid, or vitamin B9. Multiple studies have indicated that antiepileptic drugs, including gabapentin, can reduce the body’s folate levels. While gabapentin is generally well-tolerated, it may cause side effects such as drowsiness, dizziness, and coordination problems. It can also interact with certain medications, so it is important to inform the healthcare provider about all current medications and medical conditions before starting treatment. Amlodipine Interactions. There are 535 drugs known to interact with amlodipine, along with 4 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 23 are major, 474 are moderate, and 38 are minor. 270 medications are known to interact with gabapentin. Includes: drug, food, pregnancy, breastfeeding and therapeutic duplication warnings. If you take many medicines, your chances for this type of interaction increases. For example, taking two medicines that cause drowsiness at the same time can increase this side effect. Drug-food and drug-drink interactions: Food and drinks can change how medicines work or worsen side effects when they are combined. Examples include beverages Some of the main substances that interact with gabapentin are morphine, caffeine, losartan, ethacrynic acid, phenytoin, mefloquine and magnesium oxide. Some of the side effects caused by gabapentin are teratogenicity, hypoventilation, respiratory failure and myopathy. There is 1 alcohol/food/lifestyle interaction with gabapentin. Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with gabapentin. Gabapentin is primarily eliminated unchanged by the kidney. Therapy with gabapentin should be administered cautiously in patients with impaired renal function. Dosage adjustments and titration should be made in accordance with product package labeling and individual patient response. Switch to professional interaction data Moderate Food Interaction Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Immediate-release forms of gabapentin (Neurontin, generic gabapentin) can be taken with or without food. The longer-acting forms of gabapentin (Horizant, Gralise) should be taken with food or a meal to help improve the absorption of the medicine. Take Horizant tablets with food. Swallow tablets whole with a full glass of water. Don't chew, break or crush. Take other forms of gabapentin with or without food. Neurontin and generic forms of Neurontin tablets may be broken into two pieces. You can take the second half for your next dose. There are no known dietary interactions with gabapentin, which means that there aren’t any specific foods that you should absolutely avoid. In order to support brain and nerve health, a general healthy diet such as an anti-inflammatory Mediterranean diet is ideal while taking gabapentin. The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence. The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects.
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