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Reading Time: 5 minutes Living with nerve pain, fibromyalgia, or epilepsy requires effective treatment options. Gabapentin (often sold under the brand name Neurontin) and pregabalin (brand name Lyrica) are two commonly prescribed medications that work in similar ways. Gabapentin is indicated as adjunct therapy for partial seizures and postherpetic neuralgia. 4 Pregabalin is indicated for the same uses as gabapentin, plus the management of fibromyalgia and neuropathic pain associated with diabetes, specifically diabetic neuropathy. 5. In addition, pregabalin can be prescribed to treat fibromyalgia, while gabapentin is sometimes prescribed for restless legs syndrome and hot flashes in menopausal women. They may also be prescribed for other conditions as directed by your doctor. What are gabapentin and pregabalin used for? Gabapentin and pregabalin are used to treat neuropathic pain, epilepsy, and other conditions such as fibromyalgia and generalized anxiety disorder. Which medication works faster, gabapentin or pregabalin? Pregabalin generally works faster, with patients often experiencing relief within a few days. Pregabalin (Lyrica) and gabapentin (Neurontin) are both approved to treat nerve pain. How are they different, and which one is preferred? Compare both meds here. Both Pregabalin and Gabapentin treat nerve-related conditions, but they have some differences in their approved uses. Pregabalin Uses: Nerve Pain – Treats diabetic neuropathy, postherpetic neuralgia, and spinal cord injury-related pain. Fibromyalgia – Approved to relieve widespread pain and tenderness. Differences: Pregabalin vs Gabapentin Gabapentin and Pregabalin are effective pain management solutions prescribed for nerve pain and seizures. Both these medications are classified as gabapentinoids, but there are some distinctions between the two medicines. To determine whether Lyrica or gabapentin is a better option for you, your doctor will consider several factors. fibromyalgia, a long-term (chronic) condition that causes pain, fatigue (low Pregabalin is approved for additional uses, including fibromyalgia and nerve pain in certain adults. Healthcare providers commonly prescribe these medications for off-label uses (non-FDA-approved uses) as well, such as anxiety disorders. For starters, gabapentin has been on the market ten years longer, so it’s the cheaper option. On the other hand, pregabalin is FDA-approved for treating fibromyalgia pain, while gabapentin is not. Naturally, doctors prefer to prescribe medications approved for a specific condition, but other factors warrant consideration. The authors concluded that pregabalin, at a dose of 450mg daily, was most likely to be effective in treating patients with fibromyalgia, but adverse events were not negligible. Further evidence was necessary to clarify these conclusions. Gabapentin is typically taken in three daily doses that add up to between 900 mg and 2,400 mg. There is no standard dosage of gabapentin for fibromyalgia because it is an off-label use. Studies investigating the use of gabapentin for fibromyalgia used between 1,200 mg and 2,400 mg total daily dose. Pregabalin vs Gabapentin: Pregabalin is generally considered to be safer. Gabapentin, on the other hand, has been associated with a higher risk of certain side effects, such as dizziness and ataxia. However, Gabapentin's safety profile is generally considered to be better than Pregabalin's in terms of cost and availability. Gabapentin is contraindicated in individuals who have hypersensitivity to this medication or its components, which can cause fever and other symptoms that could become severe. Pregabalin vs Gabapentin â What is the Difference? Pregabalin and gabapentin can both provide relief from pain and be effective ways to manage seizure disorders. The Agency for Healthcare Research and Quality (AHRQ) review focused on seven common chronic pain conditions (neuropathic pain, fibromyalgia, osteoarthritis, inflammatory arthritis, low back pain The main differences between Lyrica and gabapentin are: Lyrica is a brand name for pregabalin. Gabapentin is a generic name - brands of gabapentin include Neurontin, Gralise, and Horizant. Gabapentin is not the same as pregabalin, even though they both belong to the same class of medicine, called gabapentinoids, and work similarly Pregabalin vs Gabapentin Which is better for nerve pain depends on the individual’s response. Pregabalin is generally faster-acting and more potent, often preferred for conditions like fibromyalgia and neuropathy, while gabapentin is effective but may require higher doses for similar results. Fernando 3 MIN READ December 31, 2024. Compare the effectiveness of gabapentin vs. pregabalin for fibromyalgia based on the experiences of 35,368 members of the fibromyalgia research community. Major Differences Between Lyrica and Gabapentin. Lyrica is approved to treat seizures, post-herpetic neuralgia, and restless legs syndrome. Lyrica is also used to treat pain linked to diabetes (i.e. diabetic peripheral neuropathy) and pain associated with fibromyalgia. Neurontin (gabapentin) and Lyrica (pregabalin) are two anticonvulsant and analgesic medications originally prescribed for the treatment of epilepsy. Neurontin was originally licensed in the United States and Canada in December 1993 for use as an adjuvant medication to treat seizures and epilepsy. Lyrica on the other hand, is a much newer drug that received approval []
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