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However, like any medication, it can come with side effects. One of those side effects that some individuals may experience is swelling. Understanding how long this swelling lasts is crucial for those taking gabapentin. This article delves into the details surrounding gabapentin-induced swelling, its causes, duration, and management strategies. Medications are a common reason for swollen ankles and feet, also called pedal edema. Amlodipine (Norvasc), gabapentin (Neurontin, Horizant, Gralise), and pregabalin (Lyrica) can cause puffy legs and ankles. Birth control pills, certain over-the-counter pain medications, and steroids are a few other culprits. Gabapentin is fairly safe when you use it correctly. It does come with some possible side effects, though. People who misuse this drug are also at risk of additional side effects. Rare but serious side effects of gabapentin include: rash, itching, or yellowing of the skin; swelling of the face and throat, a condition called angioedema; problems speaking or swallowing; changes in memory, ability to concentrate, or personality. Gabapentin may cause breathing problems in people who use opioid pain medicines and those with If I backed off to take 200 mg three times a day, I didn’t have the clinical benefit for my chronic pain syndrome. If I took 700 mg a day, I still had the side effect, so I worked out the dosing for myself: I alternate 600 mg a day and 700 mg a day by adding an extra 100 mg every other day. Other side effects may include blurred vision, amblyopia (lazy eye), dry mouth, peripheral edema (fluid retention in the feet and hands), tremor, sexual dysfunction, and gastrointestinal disturbances. Best titrated up slowly to reduce the risk of side effects; however, this may delay the onset of an effect. Edema is a well-described side effect of gabapentinoid drugs (i.e., gabapentin and pregabalin). In this study from Ontario, Canada, researchers used provincial databases to examine whether gabapentinoid use was followed by diuretic prescriptions — a so-called “prescribing cascade” in which a drug is prescribed to treat an adverse effect of another drug. Although gabapentin is generally well tolerated, 1 potential reported adverse effect is peripheral edema. However, due to the extensive number of etiologies of peripheral edema, medication causes may be overlooked on an inpatient psychiatric unit. In our case, neuralgia and hyperesthesia has been observed as new side effects. As a noticeable point, gabapentin consumption is for treatment of neuralgia, but here neuralgia is one of the gabapentin side-effects. Furthermore, localized edema is a rare side effect that we faced with severe state of it. Leg edema might be occurred in systemic Gabapentin could also cause abnormal finding of visual evoked potentials and pattern electroretinogram . It was suggested that toxic effects on the neuro-transmitter function of the optic nerve might be responsible. Macular edema on optical coherence tomography after gabapentin has not hitherto been described. Using fluorescence angiography These common side effects of gabapentin may happen in more than 1 in 100 people. They're usually mild and go away by themselves. There are things you can do to help cope with them: As your body gets used to gabapentin, these side effects should wear off. Check with your doctor immediately if any of the following side effects occur while taking gabapentin: More common in children. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Similarly, the incidence of peripheral edema caused by CCB is dose related and common in the elderly, comparable to reports of gabapentin induced edema. This case illustrates that gabapentin induced leg swelling can confound the clinical picture and it is thus important to recognize this side effect of gabapentin. Research indicates that a subset of individuals taking gabapentin may experience edema as a side effect. While comprehensive statistics are challenging to pinpoint due to varying study designs and populations, anecdotal evidence suggests that this side effect isn’t uncommon among users. It is important to recognize this adverse effect because gabapentin is used in conditions like diabetic neuropathy, which is associated with multiple co-morbidities that can give rise to bilateral leg swelling. Presence of gabapentin induced leg swelling can thus confound the clinical picture. Keywords: Edema, gabapentin, lower extremity The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. However, elderly patients are more likely to have unwanted effects (eg, problems with balance or walking, swelling in the feet or legs) and age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving gabapentin. The authors reported bilateral pretibial edema after 3 weeks of gabapentin 300 mg/d for neuropathic pain. Within 3 days of discontinuation of gabapentin, the edema resolved. When the patient was rechallenged with gabapentin, the edema returned after 5 days, suggesting the authors' suspicions of an adverse effect from gabapentin was likely correct. For those taking gabapentin, it is important to be aware of the potential side effects, including swelling or edema. Monitoring your body for any signs of edema while on gabapentin is essential for prompt intervention and prevention of complications.
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