Gabapentin can cause fluid buildup in the legs (edema), which can lead to temporary weight gain. You can also gain weight without fluid buildup, though it’s not common. You may be able to avoid weight gain from gabapentin by adjusting your diet and exercising regularly. Many individuals seek to lose weight, but does gabapentin cause weight gain? Gabapentin cause weight gain which can complicate weight loss efforts. As an anti-seizure medication, it is often used for chronic pain management, though managing gabapentin withdrawal can be part of a comprehensive weight management strategy. It’s not clear why medications like gabapentin cause weight gain, but it could be due to increased appetite. It’s important to keep in mind that not all anticonvulsants cause weight gain. Some, like lamotrigine (Lamictal), usually have no effect on body weight. And others, like topiramate (Topamax), can actually cause weight loss. 5. Gabapentin may cause weight gain by increasing your appetite, causing fluid retention, and inhibiting physical activity by causing fatigue. Because gabapentin is an anticonvulsant, it prevents seizures and nerve pain by reducing nerve activity in the central nervous system. The treatment can also stimulate appetites and serotonin levels in some individuals, which again causes overeating—weight gain. Gabapentine and Weight Gain Studies Several studies evaluated the link between Gabapentin use and weight gain. While some studies came up empty on findings, others presented solid results demonstrating the possible Although it’s uncommon, edema from gabapentin may lead to weight gain. If you experience edema or weight gain while taking gabapentin, let your prescriber know, but don’t stop taking the medication until you speak with them. This article will provide clear guidance on how to mitigate and potentially stop weight gain associated with gabapentin use, offering practical strategies and insights to help you manage this side effect effectively. Gabapentin can cause weight gain, but this side effect is usually rare. People may gain weight while taking gabapentin because the drug increases their appetite and causes water retention, mainly in the arms, hands, legs, and feet. How Gabapentin Causes Weight Gain: List of Possibilities. Gabapentin has a poorly understood mechanism of action and weight gain is uncommon. Since there is some confusion regarding the precise neurophysiological effects of the drug, it is difficult to pinpoint the specific cause of weight gain. Patients who have been prescribed gabapentin are often concerned about weight gain as a side effect. However, they should note, weight gain is a very rare side effect, observed in less than 5% of patients. In cases where weight gain does occur, it is typically a result of an increased appetite or reduced exercise caused by the drug. A 300mg dose of gabapentin can potentially cause weight gain, though not in everyone, and the likelihood can depend on individual circumstances and lifestyle factors. It’s important to monitor your own body and weight while on this medication. Gabapentin is thought to cause weight gain by increasing patients’ appetites and causing fatigue that reduces their physical activity. It can also cause water retention, with swelling (edema) of the hands, arms, feet, and legs, which may contribute to weight gain. Related: Does Trazodone cause weight gain? One study found that in patients My neurologist increased my dosage 2x, with no success. I did some research on my own and spoke to my rheumatologist and pain management doctor. They both agreed: if the lowest dose doesn't work, then it won't work It'll just cloud your mind. Yes, gabapentin can cause weight gain. One review article looking at weight gain from medications found an average weight gain of almost 5 pounds after just 1.5 months on gabapentin. Weight gain is not considered a common side effect of gabapentin. In clinical trials, only about 2% of people reported weight gain with its use. In people who do gain weight while on gabapentin, a research study showed a weight gain of about 5.5 pounds after 1.5 months of use. I have been on Gabapentin 2400 mg per day and have gained 30 pounds in a short time and just wanted to know if this med causes the weight gain or is it just due to me eating more. Answer. Yes, weight gain is a possible side effect for gabapentin (brand name Neurontin). The incidence of weight gain with gabapentin varies by product: Higher doses and longer treatment periods increase your risk of weight gain [11]. People who take Gabapentin might gain about 5 pounds after just 6 weeks of use [12]. Weight gain affected 3% of patients over 12 years old with epilepsy, compared to 2% who took a placebo [12]. To make this review of a large number of weight-affecting drugs feasible, and due to the availability of Gabapentin was associated with a weight gain of 2.2 kg
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