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GABA B receptors have a minor effect on normal relaxation of the striated urethral sphincter via motoneuron excitability ; thereby, we think that in some patients gabapentin may cause incontinence by overrelaxation of the external sphincter via excessive influence of GABA B. Gabapentin-Induced Urinary Incontinence: A Rare Side Effect in Patients with Neuropathic Pain Sibel Kibar, Sibel Demir, Nebahat Sezer, Belma Füsun Köseo L lu, These side effects can vary from person to person. It is impossible to predict how your body will react once it is exposed to this medication. Some people get away with mild side effects, while others suffer terribly. Make sure you are not using any other medication that might interact negatively with gabapentin or enhance its side effects. Urinary retention is a condition in which impaired emptying of the bladder results in postvoidal residual urine. It is generally classified into 'acute' or 'chronic' urinary retention. Because of the complex mechanism of micturition, many drugs can interact with the micturition pathway, all via diff The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. Gabapentin is a drug used to treat nerve pain and anxiety. Find out if it can cause Urinary Incontinence and other side effects. Read on to learn more about the potential risks associated with this medication. I did read somewhere that urinary retention is a side effect of gabapentin and of course as I've been in a lot more pain recently I have taken the maximum dose am allowed (or prescribed). Anyone else have this and do similar drugs to gabapentin have similar effect in some. I have noted a strong correlation of trouble urinating and taking gabapentin. I take it at night and have substantial problems urinating in the morning and for a couple of hours after I get up. This effect dissipates as the day goes on and starts again within an hour of taking my evening dose. The most common side effects of gabapentin for urinary retention include dizziness, drowsiness, and nausea. These side effects are usually mild and temporary, but in some cases, they can be more severe. Along with its needed effects, gabapentin (the active ingredient contained in Neurontin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking gabapentin: More common side effects When you stop taking gabapentin, you'll need to reduce your dose gradually to avoid withdrawal symptoms. Do not stop taking gabapentin without talking to your doctor. Talk to your doctor if you're concerned about becoming physically dependent on gabapentin. Other side effects. These are not all the side effects of gabapentin. Urinary retention (UR) is a urological syndrome characterized by the patient’s inability to empty all the urine from the bladder. It is usually caused by obstructive diseases of the lower urinary tract (eg, benign prostatic hyperplasia [BPH] and urethral stricture), urinary tract infections and/or inflammatory diseases, and neurological disorders (eg, diabetic neuropathy, multiple sclerosis Yes, gabapentin can cause urinary incontinence, though it is considered a rare side effect. While the medication is primarily known for treating nerve pain, seizures, and restless legs syndrome, some individuals may experience a disruption in their bladder control while taking it. In this way, the present case was the first to describe a subject with the recurrence of urinary incontinence with the GBP rechallenge. This adverse effect, although not potentially fatal, can be very embarrassing to patients and lead to poor compliance with therapy. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. It’s been suggested that GABA B receptor activation by gabapentin may cause relaxation of the external urethra sphincter leading to urinary incontinence and overactive bladder. In this case, it has been noted that the urinary frequency was dose-dependent, which may be related to the above phenomenon. Comment 4: “Is urinary retention a common side effect of gabapentin?” While urinary retention isn’t a common side effect, sedation caused by gabapentin can contribute to delayed urination. Mechanism : Gabapentin’s sedative properties may relax the bladder muscles or reduce the dog’s awareness of the need to urinate. Urinary retention is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Aspirin, and have Multiple sclerosis. What are gabapentin urinary side effects? Gabapentin may cause urinary side effects such as urinary retention or incontinence in some individuals. What are neurontin side effects? Neurontin (gabapentin) side effects can include dizziness, drowsiness, and weight gain, among others. Physicians who administer gabapentin should inform their patients about the potential risk of gabapentin-induced incontinence and its negative impact on quality of life. Gabapentin is a first-line agent for neuropathic pain management and has a favorable safety profile.
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